Abacavir/lamivudine, sold under the brand name Kivexa among others, is a medication used to treat HIV/AIDS. It is a fixed dose combination of abacavir and lamivudine. It is generally recommended for use with other antiretrovirals. It is commonly used as part of the prefered treatment in children. It is taken by mouth as a tablet.

Common side effects include trouble sleeping, headache, depression, feeling tired, nausea, rash, and fever. Serious side effects may include high blood lactate levels, allergic reactions, and enlargement of the liver. It is not recommended in people with a specific gene known as HLA-B*5701. Safety in pregnancy has not been well studied but it appears to be okay. Lamivudine and abacavir are both nucleoside reverse transcriptase inhibitors (NRTI)

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